Expression of trefoil factors and TWIST1 in colorectal cancer and their correlation with metastatic potential and prognosis

doi:10.3748/wjg.v23.i1.110

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 23, Issue 1

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7762)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-5) series.

Item

Count

PDF

558

WORD

180

HTML

4291

Figures (1-3)

298

Tables (1-5)

222

Sum=5549

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

846

Download

1367

Sum=2213

Jan 7, 2017 (publication date) through Dec 24, 2024

Times Cited of This Article

Times Cited (26)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Jan 7, 2017; 23(1): 110-120
Published online Jan 7, 2017. doi: 10.3748/wjg.v23.i1.110

Table 4 Correlation between TFF1, TFF3, and TWIST1 expression and clinicopathological Characteristics of colorectal cancers n (%)

Characteristicn = 75	TFF1			TFF3			TWIST1
Characteristicn = 75	Low	High	P value	Low	High	P value	Low	High	P value
Age (yr)			0.299			0.368			0.840
≤ 60	28 (63.6)	17 (54.8)		27 (57.4)	18 (64.3)		31 (60.8)	14 (58.3)
> 60	16 (36.4)	14 (45.2)		20 (42.6)	10 (35.7)		20 (39.2)	10 (41.7)
Gender			0.369			0.146			0.134
Male	30 (68.2)	18 (58.1)		33 (70.2)	15 (53.6)		30 (58.8)	18 (75.0)
Female	14 (31.8)	13 (41.9)		14 (29.8)	13 (46.4)		21 (41.2)	6 (25.0)
Histology			0.089			0.475			0.397
Adenocarcinoma	42 (95.5)	26 (83.9)		42 (89.4)	26 (92.9)		47 (92.2)	21 (87.5)
Mucinous	2 (4.5)	5 (16.1)		5 (10.6)	2 (7.1)		4 (7.8)	3 (12.5)
Differentiation			0.029			0.136			0.234
Well	10 (22.7)	12 (38.7)		15 (31.9)	7 (25.0)		18 (35.3)	4 (16.7)
Moderate	16 (36.4)	15 (48.4)		22 (46.8)	9 (32.1)		20 (39.2)	11 (45.8)
Poor	18 (40.9)	4 (12.9)		10 (21.3)	12 (42.9)		13 (25.5)	9 (37.5)
Location			0.802			0.411			0.847
Colon	31 (70.5)	21 (67.7)		31 (66.0)	21 (75)		35 (68.6)	17 (70.8)
Rectum	13 (29.5)	10 (32.3)		16 (34.0)	7 (25)		16 (31.4)	7 (30.7)
T			0.545			0.651			0.246
1	2 (4.5)	0		1 (2.1)	1 (3.6)		1 (2.0)	1 (4.2)
2	10 (22.7)	9 (29.0)		14 (29.8)	5 (17.9)		16 (31.4)	3 (12.5)
3	13 (29.5)	7 (22.6)		11 (23.4)	9 (32.1)		11 (21.6)	9 (37.5)
4	19 (43.2)	15 (48.4)		21 (44.7)	13 (46.4)		23 (45.1)	11 (45.8)
N			0.143			0.034			0.000
No	26 (59.1)	13 (41.9)		20 (42.6)	19 (67.9)		34 (66.7)	5 (20.8)
Yes	18 (40.9)	18 (58.1)		27 (57.4)	9 (32.1)		17 (33.3)	19 (79.2)
M			0.484			0.267			0.288
No	41 (93.2)	28 (90.3)		42 (89.4)	27 (96.4)		48 (94.1)	21 (87.5)
Yes	3 (6.8)	3 (9.7)		5 (10.6)	1 (3.6)		3 (5.9)	3 (12.5)
Staging			0.917			0.031			0.003
I	9 (20.5)	6 (19.4)		11 (23.4)	4 (14.3)		13 (25.5)	2 (8.3)
II	17 (38.6)	10 (32.3)		11 (23.4)	16 (57.1)		23 (45.1)	4 (16.7)
III	15 (34.1)	12 (38.7)		20 (42.6)	7 (25.0)		12 (23.5)	15 (62.5)
IV	3 (6.8)	3 (9.7)		5 (10.6)	1 (3.6)		3 (5.9)	3 (12.5)

CRC: Colorectal cancer; MNT: Matched normal tissue; MLN: Metastatic lymph node; Liver M: Liver metastasis.

Citation: Yusup A, Huji B, Fang C, Wang F, Dadihan T, Wang HJ, Upur H. Expression of trefoil factors and TWIST1 in colorectal cancer and their correlation with metastatic potential and prognosis. World J Gastroenterol 2017; 23(1): 110-120
URL: https://www.wjgnet.com/1007-9327/full/v23/i1/110.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i1.110