Copyright
©The Author(s) 2016.
World J Gastroenterol. Mar 7, 2016; 22(9): 2779-2788
Published online Mar 7, 2016. doi: 10.3748/wjg.v22.i9.2779
Published online Mar 7, 2016. doi: 10.3748/wjg.v22.i9.2779
Figure 4 Gadd45a inhibits hepatic fibrosis through the suppression of transforming growth factor-β/Smad signaling.
A: Effects of Gadd45 on PAI-1-Luc activity in HSCs treated with pcDNA3.1, Gadd45a, and Gadd45a siRNA in both the CCl4 and saline groups; B: Effects of Gadd45 on (CAGA)9 MLP-Luc activity in HSCs treated with pcDNA3.1, Gadd45a, and Gadd45a siRNA in both the CCl4 and saline groups. HSC: Hepatic stellate cell; TGF: Transforming growth factor.
- Citation: Hong L, Sun QF, Xu TY, Wu YH, Zhang H, Fu RQ, Cai FJ, Zhou QQ, Zhou K, Du QW, Zhang D, Xu S, Ding JG. New role and molecular mechanism of Gadd45a in hepatic fibrosis. World J Gastroenterol 2016; 22(9): 2779-2788
- URL: https://www.wjgnet.com/1007-9327/full/v22/i9/2779.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i9.2779