Impact of non-oncological factors on tumor recurrence after liver transplantation in hepatocellular carcinoma patients

Table 3 Studies comparing the effects of recipient and donor characteristics on tumor recurrence among patients with hepatocellular carcinoma after liver transplantation

Ref.	Year	Characteristics	Evaluated parameter	Recurrence rate	P value
Recipient
Mathur et al[59]	2014	Overweight or obese	Overweight vs obese vs non-obese	15% vs 15% vs 7%	< 0.050
Ballarin et al[70]	2011	Age	Elderly vs younger	7.1% vs 4.8%	> 0.050
Yang et al[73]	2014	Gender	Male vs female	NA	NA
Donor
Nagai et al[74]	2014	Ischemia times	CIT >10 h vs < 10 h and WIT > 50 min vs ≤ 50 min	NA	0.015
Sharma et al[85]	2012	Age	Median donor age for patients with HCC recurrence vs without HCC recurrence	NA	0.008
Miyagi et al[94]	2012	ABO-I graft	Strong imunosuppressive therapy vs other imunosuppressive therapy	NA	NA
Teng da et al[96]	2012	Steatosis donor liver	Grafts with no steatosis vs mild steatosis vs moderate-to-severe steatosis	15.8% vs 8.3% vs 33.3% at 1 yr; 28.7% vs 20.8% vs 50% at 3 yr	> 0.050

CIT: Cold ischemia times; WIT: Warm ischemia times; HCC: Hepatocellular carcinoma; ABO-I: ABO-incompatible; NA: Not analyzed.