Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats

doi:10.3748/wjg.v22.i8.2558

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Feb 28, 2016 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2016; 22(8): 2558-2565
Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2558

Table 3 mRNA expression and proliferating cell nuclear antigen immunohistochemistry

Group	n	HMGB1	TLR4	NF-κB	Caspase-3	PCNA (%)
Control	10	0.01 ± 0.01	0.04 ± 0.02	0.49 ± 0.25	1.36 ± 0.26	7.48 ± 0.90
Model	20	0.25 ± 0.04^a	0.41 ± 0.22^a	2.68 ± 1.35^a	3.41 ± 0.85^a	17.55 ± 2.40
SNMC	20	0.11 ± 0.04^b	0.22 ± 0.08^b	1.78 ± 0.64^b	2.57 ± 1.04^b	25.57 ± 2.94^b
IPTT	20	0.06 ± 0.03^b^c	0.07 ± 0.02^b^c	0.74 ± 0.41^b^c	1.61 ± 0.45^b^c	36.34 ± 4.91^b^c

^aP < 0.05 vs control group;

^bP < 0.05 vs model group; and

^cP < 0.05 vs SNMC group. HMGB: High mobility group box; TLR: Toll-like receptor; NF: Nuclear factor; PCNA: Proliferating cell nuclear antigen; Control group: Negative control group; Model group: Injected with D-GalN; SNMC group: Injected with D-GalN and treated with SNMC.

Citation: Zhang Y, Luo JX, Hu XY, Yang F, Zhong S, Lin W. Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats. World J Gastroenterol 2016; 22(8): 2558-2565
URL: https://www.wjgnet.com/1007-9327/full/v22/i8/2558.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i8.2558