Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer

Table 2 Correlation coefficients (r) between levels of SphK1, LPAR2, and each S1P receptor

		LPAR2	SPHK1	S1PR1	S1PR2	S1PR3
LPAR2	Pearson correlation	1	0.7841	0.6381	0.6391	0.620
	Sig. (2-tailed)		0.000	0.000	0.000	0.001
SPHK1	Pearson correlation	0.7841	1	0.6611	0.577	0.553
	Sig. (2-tailed)	0.000	.	0.000	0.002	0.003
S1PR1	Pearson correlation	0.6381	0.6611	1	0.587	0.8151
	Sig. (2-tailed)	0.000	0.000	.	0.001	0.000
S1PR2	Pearson correlation	0.6391	0.577	0.587	1	0.576
	Sig. (2-tailed)	0.000	0.002	0.001	.	0.002
S1PR3	Pearson correlation	0.620	0.553	0.8151	0.576	1
	Sig. (2-tailed)	0.001	0.003	0.000	0.002	.

¹Correlation is significant at the 0.01 level (2-tailed).