Mutation analysis of 13 driver genes of colorectal cancer-related pathways in Taiwanese patients

Table 4 Correlation between clinicopathological features and APC mutation and two or more driver genes mutations

		Mutation of APC				Mutations of two or more driver genes
		No	Yes	Total	P value	No	Yes	Total	P value
Gender	F	27	10	37	0.503	23	14	37	0.435
	M	52	14	66		46	20	66
Grade	Well	4	3	7	0.443	4	3	7	0.579
	Moderate	67	19	86		57	29	86
	Poor	8	2	10		8	2	10
LN	-	32	17	49	0.009	28	21	49	0.043
	+	47	7	54		41	13	54
Stage	I, II	30	16	46	0.013	27	19	46	0.108
	III, IV	49	8	57		42	15	57

P value by χ² test.