Human urokinase-type plasminogen activator gene-modified bone marrow-derived mesenchymal stem cells attenuate liver fibrosis in rats by down-regulating the Wnt signaling pathway

Figure 5 Effect of urokinase plasminogen activator gene modified-bone marrow-derived mesenchymal stem cells transplantation on the protein expression of molecules of the Wnt signaling pathway. A: Representative Western blot analysis of uPA, β-catenin, Wnt4, and Wnt5a protein expression levels in four groups; B: The bar graph represents mean relative protein expression levels of urokinase plasminogen activator, β-catenin, Wnt4, and Wnt5a. Data are normalized to GAPDH protein expression levels. GAPDH: Glyceraldehyde 3-phosphate dehydrogenase; BMSCs: Bone marrow-derived mesenchymal stem cells; uPA: Urokinase plasminogen activator.