Human urokinase-type plasminogen activator gene-modified bone marrow-derived mesenchymal stem cells attenuate liver fibrosis in rats by down-regulating the Wnt signaling pathway

Figure 4 Effect of urokinase plasminogen activator gene modified-bone marrow-derived mesenchymal stem cells transplantation on the mRNA expression of molecules of the Wnt signaling pathway. The bar graph shows mean relative mRNA expression levels of β-catenin, Wnt4 and Wnt5a in liver tissues. Each sample was repeated three times from each cluster. Data are normalized to GAPDH mRNA expression levels. GAPDH: Glyceraldehyde 3-phosphate dehydrogenase; BMSCs: Bone marrow-derived mesenchymal stem cells; uPA: Urokinase plasminogen activator.