Interleukin-22 contributes to liver regeneration in mice with concanavalin A-induced hepatitis after hepatectomy

Figure 5 Hepatic alpha fetal protein mRNA expression in the remnant liver after partial hepatectomy. A, B: Alpha fetal protein (AFP) mRNA expression began to increase at 32 h and significantly increased to peak at 48 h after hepatectomy. With the interleukin (IL)-22 pretreatment, the AFP mRNA levels significantly increased at 32 h after partial hepatectomy compared with the concanavalin A (ConA) + PHX group (^aP < 0.05), and marked increases were observed at 40 h, 48 h and 1 wk (^cP < 0.01). However, the difference was not significant at 2 wk (P > 0.05).