Interleukin-22 contributes to liver regeneration in mice with concanavalin A-induced hepatitis after hepatectomy

Figure 4 Proliferating cell nuclear antigen labeling indices in the remnant livers after partial hepatectomy. A: Compared with the concanavalin A (ConA) + PHX group, the proliferating cell nuclear antigen (PCNA) labeling indices were significantly increased in the ConA, PHX and ConA + PHX + interleukin (IL)-22 groups at all of the time points (^aP < 0.05), particularly at 32, 40, and 48 h (^cP < 0.01). Furthermore, the increases in the PCNA levels in the ConA + PHX + IL-22 group were significantly greater than those in the ConA and PHX groups at 32 h, 40 h and 48 h (^aP < 0.05); B: PCNA labeling of the cells at 32 h and 48 h after hepatectomy in the PHX, ConA, ConA + PHX and ConA + PHX + IL-22 groups, respectively.