Role of a liver-first approach for synchronous colorectal liver metastases

Table 3 Characteristics of 18 patients who underwent the formalized treatment plan

Patient	Largest size (cm)	CEA level (μg/L)	cTN	No. of mets	CTx	Responseon CTx	Liver surgery	RTx	Primary surgery
1	16	861.4	cT3N1	1	Xelox	PD	Hemihep	None	Left Hemicol
2	2	1	cT4N2	4	Folfox	PR	Extended hemihep	None	LAR
3	3.5	13.4	cT4N1	1	None	None	Partial	30 Gy/Xeloda	LAR
4	6	113.4	cT3N1	5	Folfox	SD	Partial	None	Left Hemicol
5	2.5	16.8	cT3N1	6	Xelox	PR	Extended hemihep	30 Gy/Xeloda	None
6	7.9	30.4	cT4N1	4	Xelox	PR	Extended hemihep	None	LAR
7	4	3.2	cT2N1	3	Folifiri + Cet	PR	Hemihep	None	LAR
8	2.4	2.4	cT3N2	3	Folifiri + Cet	PR	Partial	50 Gy/Xeloda	LAR
9	5	78.1	cT4N2	1	None	None	Partial	50 Gy/Xeloda	APR
10	3.8	160.9	cT3N2	1	Folfox	SD	Partial	None	APR
11	4	3.7	cT3N0	6	Folifiri + Cet	PR	Partial	30 Gy/Xeloda	LAR
12	1.5	19.7	cT3N1	4	Folfox + Bev	PR	Partial	None	LAR
13	8.5	87.2	cT3N1	5	None	None	Partial	None	LAR
14	12	22.1	cT4N1	6	Folfox + Cet	PR	Hemihep	None	LAR
15	6	79.4	cT3N1	3	Folfoxiri	SD	Extended hemihep	None	LAR
16	4.3	6.1	cT3N0	12	Xelox + Bev	PR	Partial	None	LAR
17	3	34.7	cT3N1	2	None	None	Partial	None	LAR
18	3.5	39.0	cT3N2	6	Xelox	SD	Extended hemihep	50 Gy/Xeloda	None

LAR: Low anterior resection; APR: Abdominal perineal resection; Hemihep: Hemihepatectomy; Hemicol: Hemicolectomy; Partial: Partial hepatectomy; Cet: Cetuximab; Bev: Bevacizumab; xelox: Oxaliplatin plus capecitabine; Folfox: Oxaliplatin, leucovorin and 5-FU; Folfiri: Irinotecan, leucovorin and 5-FU; Folfoxiri: Oxaliplatin, irinotecan, leucovorin and 5-FU.