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©The Author(s) 2016.
World J Gastroenterol. Feb 14, 2016; 22(6): 2071-2080
Published online Feb 14, 2016. doi: 10.3748/wjg.v22.i6.2071
Published online Feb 14, 2016. doi: 10.3748/wjg.v22.i6.2071
Table 1 Tumor development in mice coinjected with NICD/IDH1R132C, NICD/shP53, shP53/IDH1R132C or NICD/shP53/IDH1R132C
| Code | Sex | Age (wk) | WPI | Tumor1 | Tumor number | Tumor size (mm) | |
| NICD/IDH1R132C | ND-F4.1 | F | 28 | 21 | N | 0 | 0 |
| ND-F4.2 | F | 28 | 22 | N | 0 | 0 | |
| ND-F4.3 | F | 28 | 22 | N | 0 | 0 | |
| ND-F4.4 | F | 28 | 22 | N | 0 | 0 | |
| NICD/shP53 | NP-F4.1 | F | 31 | 24 | N | 0 | 0 |
| NP-F4.2 | F | 31 | 24 | N | 0 | 0 | |
| NP-F4.3 | F | 31 | 24 | N | 0 | 0 | |
| NP-F4.4 | F | 31 | 24 | N | 0 | 0 | |
| shP53/IDH1R132C | PD-F3.1 | F | 27 | 20 | N | 0 | 0 |
| PD-F3.2 | F | 27 | 20 | N | 0 | 0 | |
| PD-F3.3 | F | 27 | 20 | N | 0 | 0 | |
| NICD/shP53/IDH1R132C | NDP-F4.1 | F | 16 | 9 | N | 0 | 0 |
| NDP-F4.2 | F | 19 | 12 | Y | 1 | 1.5 | |
| NDP-F4.3 | F | 19 | 12 | Y | 2 | 1, 2 | |
| NDP-F4.4 | F | 20 | 13 | Y | 2 | 1, 1 | |
| NDP-F4.5 | F | 20 | 13 | Y | 4 | 1, 1, 2, 3 | |
| NDP-F4.6 | F | 22 | 15 | Y | 3 | 1.5, 2, 2 | |
| NDP-F4.7 | F | 22 | 15 | Y | 5 | 1, 1.5, 2, 2, 3 | |
| NDP-F4.8 | F | 25 | 18 | Y | 6 | 1, 2, 2.5, 4, 4, 6 | |
| NDP-F4.9 | F | 25 | 18 | Y | 4 | 1, 1, 2, 4 |
- Citation: Ding N, Che L, Li XL, Liu Y, Jiang LJ, Fan B, Tao JY, Chen X, Ji JF. Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice. World J Gastroenterol 2016; 22(6): 2071-2080
- URL: https://www.wjgnet.com/1007-9327/full/v22/i6/2071.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i6.2071