Association between serum α-L-fucosidase and non-alcoholic fatty liver disease: Cross-sectional study

Table 1 Comparison of clinical characteristics between subjects with and without non-alcoholic fatty liver disease

Variable	With NAFLD	Without NAFLD	t value	P value
Age (yr)	47.9 (10.3)	44.3 (11.2)	20.844	< 0.001
Gender (male/female, n)	4616/1647	4840/5370	1097.9281	< 0.0011
BMI (kg/m2)	26.1 (2.9)	22.5 (2.7)	80.032	< 0.001
WC (cm)	90.7 (8.2)	79.7 (8.5)	80.773	< 0.001
SBP (mmHg)	134.2 (17.5)	123.1 (17.1)	39.998	< 0.001
DBP (mmHg)	82.3 (11.1)	74.6 (11.2)	42.506	< 0.001
WBC (109/L)	6.41 (1.6)	5.83 (1.5)	23.672	< 0.001
UA (mmol/L)	369.8 (87.8)	303.3 (81.2)	49.434	< 0.001
FBG (mmol/L)	5.00 (4.66-5.49)	4.72 (4.46-5.01)	30.8582	< 0.0012
TG (mmol/L)	1.70 (1.20-2.45)	1.00 (0.73-1.43)	44.9602	< 0.0012
TC (mmol/L)	4.9 (0.9)	4.62 (0.9)	22.188	< 0.001
LDL-C (mmol/L)	2.7 (0.7)	2.6 (0.6)	13.685	< 0.001
HDL-C (mmol/L)	1.1 (0.3)	1.3 (0.3)	39.894	< 0.001
AFU (U/L)	28.7 (7.9)	26.0 (7.3)	22.591	< 0.001
ALT (U/L)	25 (18-37)	16 (11-22)	30.3962	< 0.0012
AST (U/L)	22 (18-27)	19 (16-22)	16.9162	< 0.0012
GGT (U/L)	34 (22-57)	17 (12-28)	27.7532	< 0.0012
Cholinesterase (U/L)	9537 (1579)	8315 (1585)	48.125	< 0.001
ALP (U/L)	68 (20.1)	61 (19.9)	19.818	< 0.001
AFP (μg/L)	2.6 (2.0-3.5)	2.4 (1.8-3.4)	0.2102	< 0.8412

¹χ² value;

²Z value. Data are expressed as mean ± SD or median (IQR). NAFLD: Non-alcoholic fatty liver disease; BMI: Body mass index; WC: Waist circumference; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; WBC: White blood cell; UA: Uric acid; FBG: Fasting blood glucose; TG: Triglyceride; TC: Total cholesterol; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol; AFU: α-L-fucosidase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-Glutamyltransferase; ALP: Akaline phosphatase; AFP: Alpha-fetoprotein.