Regulating effect of TongXie-YaoFang on colonic epithelial secretion via Cl- and HCO3- channel

Figure 1 Comparison of basic electrophysiological properties of colonic mucosa in rats and 5-HT-induced the changes of short-circuit current among three groups. A-C: The basic Isc, basic voltage and basic resistance did not differ significantly between three groups, respectively (P > 0.05, respectively); D: TXYF-formula significantly increased 5-HT-induced ∆Isc in neonatal maternal separation plus restraint stress (NMS + RS) rats. ^bP < 0.01 vs NMS + RS group. Isc: The short-circuit current; ∆Isc: The changes of Isc; TXYF: TongXie-YaoFang; NMS: Neonatal maternal separation; RS: Restraint stress; NH: No handlings as control.