Gastric adenocarcinoma of the fundic gland (chief cell-predominant type): A review of endoscopic and clinicopathological features

Table 1 Clinical characteristics of previously reported cases

Author (yr)	Number of patients	Sex (M:F)	Age (yr, average)	Race or nationality	Clinical symptoms	Therapeutic method	Survival time (mo, average)	Outcome
Tsukamoto et al[4] (2007)	1	F	82	Japanese	No symptom	EMR	ND	ND
Ueyama et al[5] (2010)	10	6:4	65.5 (42-79)	Japanese: 10	ND	EMR: 2	37.1 (10-70)	Alive, NED: 10
						ESD: 5
						Operation: 3
Fukatsu et al[6] (2011)	1	M	56	Japanese	No symptom	EAM	12	Alive, NED
Terada et al[7] (2011)	1	M	78	Japanese	Abdominal pain (colon cancer)	No therapy (only biopsy)	3	Died (colon cancer)
Park et al[8] (2012)	3	3:0	65.3 (47-76)	Korean: 3	ND	ESD: 1	24.3 (11-32)	Alive, NED: 3
						Operation: 1
						Operation after ESD: 1
Singhi et al[9] (2012)	10	4:6	64.2 (44-79)	Hispanic: 4	GERD: 10	polypectomy: 10	15.4 (6-39)	Alive, NED: 8
				Caucasian: 2				Alive, persistence: 1 ND: 1
				African American: 2
				Chinese: 1
				Unknown: 1
Chen et al[10] (2012)	1	M	79	Caucasian	GERD	EMR	2	Alive, NED
					Esophageal stricture
Abe et al[11] (2013)	1	F	71	Japanese	No symptom	EMR	12	Alive, NED
Ueyama et al[12] (2014)	10	6:4	66.5 (55-78)	Japanese: 10	ND	EMR: 2	13.2 (1-19)	Alive, NED: 10
						ESD: 8
Miyazawa et al[13] (2015)	5	3:2	72.2 (67-78)	Japanese: 5	No symptom: 5	ESD: 4	19.4 (10-28)	Alive, NED: 5
						Operation after ESD: 1
Parikh et al[14] (2015)	1	M	66	Caucasian	Heartburn (GERD)	EMR	ND	Alive, NED
Kato et al[15] (2015)	1	M	80s	Japanese	ND	CLEAN-NET	3	Alive, NED
Fujii et al[16] (2015)	1	F	64	Japanese	ND	ESD	ND	ND

CLEAN-NET: Combination of laparoscopic and endoscopic approaches to neoplasia with non-exposure technique; EAM: Endoscopic aspiration mucosectomy; EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection; F: Female; M: Male; GERD: Gastroesophageal reflux disease; NED: No evidence of disease; ND: Not described.