Hepatosplenic T-cell lymphoma in a 47-year-old Crohn’s disease patient on thiopurine monotherapy

Table 1 Results of our patient

A: laboratory findings			B: immunophenotyping of liver and bone marrow biopsy
Analysis (Unit)	Results	Reference value	Immunophenotype	Results	Typical HSTCL[1,3]
White blood cell count (× 109/L)	4.6	4.0-10.0	CD 2 and 3	+	+
Platelet count (× 109/L)	42	150-400	CD 4 and 5	-	-
Hemoglobin (mmol/L)	7.7	8.5-11.0	CD 7	+	+/-
Bilirubin (μmol/L)	175	0-17	CD 8	+/-	-
ALP (IU/L)	265	0-125	CD 16	-	+/-
GGT (IU/L)	154	0-45	CD 56	+	+
ASAT (IU/L)	250	0-34	γδ-T-cell receptor	+	+
ALAT (IU/L)	437	0-44	TIA	-	+
LDH (IU/L)	701	0-247

ALP: Alkaline phosphatase; ASAT: Aspartate transaminase; ALAT: Alanine transaminase; GGT: γ-glutamyl- transferase; LDH: Lactate dehydrogenase; TIA: T-cell restricted intracellular antigen.