Copyright
©The Author(s) 2016.
World J Gastroenterol. Dec 21, 2016; 22(47): 10440-10449
Published online Dec 21, 2016. doi: 10.3748/wjg.v22.i47.10440
Published online Dec 21, 2016. doi: 10.3748/wjg.v22.i47.10440
Table 4 Relationship between endoscopic gastric mucosal atrophy and plasma ghrelin level
Mucosal atrophy | Non-atrophy | Mild atrophy | Moderate atrophy | Severe atrophy | P value |
Number | 32 | 15 | 29 | 32 | |
Male/female (n/n) | 19/13 | 10/5 | 19/10 | 20/12 | 0.969 |
Age (yr) | 67.5 ± 11.8 | 64.5 ± 12.3 | 71.9 ± 10.9 | 69.3 ± 10.0 | 0.293 |
Body weight (kg) | 50.7 ± 12.0 | 53.6 ± 10.5 | 50.6 ± 11.4 | 51.5 ± 11.4 | 0.708 |
BMI (kg/m2) | 19.9 ± 3.4 | 20.3 ± 2.8 | 20.1 ± 3.6 | 20.6 ± 3.9 | 0.896 |
Albumin (g/dL) | 3.5 ± 0.3 | 3.5 ± 0.3 | 3.3 ± 0.4 | 3.4 ± 0.5 | 0.351 |
Total cholesterol (mg/dL) | 166.4 ± 34.8 | 159.9 ± 34.9 | 153.6 ± 37.5 | 151.4 ± 40.4 | 0.510 |
Cholinesterase (U/L) | 246.0 ± 104.3 | 250.5 ± 77.7 | 201.9 ± 59.3 | 218.6 ± 77.6 | 0.283 |
Acyl-ghrelin (fmol/mL) | 39.4 ± 22.2 | 24.5 ± 23.1a | 20.2 ± 14.9a | 18.3 ± 11.8a | < 0.001 |
Desacyl-ghrelin (fmol/mL) | 345.7 ± 183.7 | 276.1 ± 169.4 | 212.6 ± 129.4a | 196.8 ± 104.4a | < 0.001 |
Pepsinogen I (ng/mL) | 525.9 ± 316.6 | 461.9 ± 330.3 | 284.2 ± 207.3a | 181.0 ± 198.8a | < 0.001 |
Pepsinogen II (ng/mL) | 45.9 ± 23.8 | 49.3 ± 32.0 | 45.8 ± 40.8 | 36.3 ± 31.6 | 0.120 |
Pepsinogen I/II | 11.6 ± 4.7 | 10.0 ± 4.6 | 6.9 ± 3.4a | 5.3 ± 3.3a | < 0.001 |
- Citation: Ichikawa H, Sugimoto M, Sakao Y, Sahara S, Ohashi N, Kato A, Sugimoto K, Furuta T, Andoh A, Sakao T, Yasuda H. Relationship between ghrelin, Helicobacter pylori and gastric mucosal atrophy in hemodialysis patients. World J Gastroenterol 2016; 22(47): 10440-10449
- URL: https://www.wjgnet.com/1007-9327/full/v22/i47/10440.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i47.10440