High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound

Table 2 Utilization of deep sedation vs general anesthesia and oxygenation during deep sedation between eras

Anesthesia type	Era 1	Era 2	Era 3	P value
DS, n (%)	41 (65.1)	73 (83.0)	61 (70.1)	0.033
GA, n (%)	22 (34.9)	15 (17.0)	26 (29.9)	0.033
DS only SpO2 nadir,	4.5 (98.0)	3.0 (99.0)a	4.0 (96.0)	< 0.001

There was a significantly lower utilization of GA in era 2 compared to era 1 (P = 0.012) that persisted as a trend only between eras 2 and 3 after Bonferroni correction (P = 0.045). There was a significantly lower median SpO₂ nadir in era 3 compared to era 2 (^aP < 0.001) that was a trend between eras 1 and 2 after Bonferroni correction (P = 0.028). DS: Deep sedation; GA: General anesthesia.