Fecal microbial transplant for the treatment of pediatric inflammatory bowel disease

Table 3 Rates of resolution of recurrent Clostridium difficile infection using fresh vs frozen fecal microbial transplant

Ref.	Fresh, n	Frozen, n	Fresh FMT resolution rate	Frozen/prepared FMT resolution rate
Hamilton et al[28], 2012	12	21	19/21	11/12
			90.5%	91.6%
Petrof et al[29], 2013	1	2	N/A	100%
			100%	100%
Lee et al[27], 2016	87 (PP)	91 (PP)	74/87, 85.1% (PP)	76/91, 83.5% (PP)
	111 (mITT)	108 (mITT)	78/111, 70.3% (mITT)	81/108, 75.0% (mITT)

PP: Per-protocol (patients received ≤ 2 same-modality FMT treatments with no Clostridium difficile infection (CDI) antibiotics administered between treatments, and no systemic antibiotics administered throughout study period; mITT: Modified intention-to-treat protocol (randomized patients; (1) received ≥ 1 same-modality FMT treatment but required antibiotics for CDI between administrations; (2) received different modality FMT treatments and did not complete follow-up period; or (3) required systemic antibiotic therapy for other infections throughout study protocol).