Non-invasive evaluation of liver stiffness after splenectomy in rabbits with CCl4-induced liver fibrosis

doi:10.3748/wjg.v22.i46.10166

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2016; 22(46): 10166-10179
Published online Dec 14, 2016. doi: 10.3748/wjg.v22.i46.10166

Table 5 Cutoff and performance values of elastography point quantification for diagnosis of liver fibrosis stages

Parameter	F0-F1 vs F2-F4	F0-F2 vs F3-F4	F0-F3 vs F4
AUROC	0.931 (0.849-0.977)	0.969 (0.901-0.995)	0.925 (0.841-0.973)
Optimal cutoff value	11.27	14.89	18.21
Sensitivity (%)	82.5 (70.1-91.3)	87.8 (73.8-95.9)	88.0 (68.8-97.5)
Specificity (%)	94.7 (74.0-99.9)	94.3 (80.8-99.3)	84.3 (71.4-93.0)
PPV (%)	97.9 (88.9-99.9)	94.7 (82.3-99.4)	73.3 (54.1-87.7)
NPV (%)	64.3 (44.1-81.4)	86.8 (71.9-95.6)	93.5 (82.1-98.6)

PPV: Positive predictive values; NPV: Negative predictive value.

Citation: Wang MJ, Ling WW, Wang H, Meng LW, Cai H, Peng B. Non-invasive evaluation of liver stiffness after splenectomy in rabbits with CCl₄-induced liver fibrosis. World J Gastroenterol 2016; 22(46): 10166-10179
URL: https://www.wjgnet.com/1007-9327/full/v22/i46/10166.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i46.10166