Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation

Figure 1 Histopathologic evaluation of explanted liver with Garcinia Cambogia associated fulminant hepatitis. A: Histopathologic examination demonstrates large areas of panacinar necrosis with complete hepatocyte dropout, collapsed lobules, florid ductular reaction, and predominantly lymphocytic infiltrates (hematoxylin-eosin stain, original magnification × 200); B: Non-necrotic areas demonstrate hepatocyte ballooning, cholestasis, and mild lymphocytic infiltration. Occasional apoptotic hepatocytes (acidophil bodies) were present (hematoxylin-eosin stain, original magnification × 400).