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©The Author(s) 2016.
World J Gastroenterol. Dec 7, 2016; 22(45): 9994-10001
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.9994
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.9994
Table 2 Hazard ratio of death as a function of preoperative fibrinogen plasma level (mg/dL) for the 652 patients under study1
Survival | Tumour-related survival | |||
HR (95%CI) | P value | HR (95%CI) | P value | |
Age (yr) | < 0.001 | < 0.001 | ||
> 68.8 vs ≤ 68.8 | 2.55 (1.91-3.40) | 2.13 (1.47-3.09) | ||
Gender | 0.298 | 0.155 | ||
Male vs female | 1.16 (0.88-1.53) | 1.31 (0.90-1.89) | ||
Tumour location | 0.368 | 0.928 | ||
Rectum vs colon | 1.19 (0.82-1.72) | 0.98 (0.59-1.61) | ||
Type of surgery | 0.180 | 0.805 | ||
Urgent vs elective | 1.42 (0.85-2.38) | 0.92 (0.49-1.74) | ||
Type of resection (R) | < 0.001 | < 0.001 | ||
R1 vs R0 | 1.98 (0.77-5.07) | 4.39 (1.61-11.97) | ||
R2 vs R0 | 2.93 (1.82-4.71) | 6.46 (3.63-11.49) | ||
Depth of invasion (pT)1 | < 0.001 | < 0.001 | ||
pT2 vs pT1 | 1.51 (0.59-3.86) | 7.53 (0.88-64.83) | ||
pT3 vs pT1 | 1.97 (0.93-4.13) | 6.03 (0.81-44.63) | ||
pT4a vs pT1 | 4.06 (1.90-8.68) | 14.99 (2.02-111.57) | ||
pT4b vs pT1 | 2.88 (1.30-6.37) | 15.55 (2.07-117.09) | ||
Node involvement (pN)1 | < 0.001 | 0.135 | ||
pN1 vs pN0 | 1.33 (0.94-1.87) | 1.51 (0.97-2.37) | ||
pN2 vs pN0 | 2.45 (1.69-3.54) | 1.59 (0.94-2.67) | ||
Systemic metastasis (M) | < 0.001 | < 0.001 | ||
M1a vs M0 | 2.62 (1.72-3.99) | 4.72 (2.72-8.19) | ||
M1b vs M0 | 1.88 (1.06-3.30) | 2.59 (1.32-5.06) | ||
Fibrinogen plasma value | 0.355 | 0.313 | ||
> 400 vs ≤ 400 | 1.15 (0.86-1.54) | 0.82 (0.54-1.21) |
- Citation: Pedrazzani C, Mantovani G, Salvagno GL, Baldiotti E, Ruzzenente A, Iacono C, Lippi G, Guglielmi A. Elevated fibrinogen plasma level is not an independent predictor of poor prognosis in a large cohort of Western patients undergoing surgery for colorectal cancer. World J Gastroenterol 2016; 22(45): 9994-10001
- URL: https://www.wjgnet.com/1007-9327/full/v22/i45/9994.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i45.9994