Preoperative evaluation of pancreatic ductal adenocarcinoma with synchronous liver metastasis: Diagnosis and assessment of unresectability

Table 8 Survival data from published studies with simultaneous resections of primary pancreatic ductal adenocarcinoma and synchronous liver metastasis

	Simultaneous resections		Palliative surgical bypass or chemotherapy		Pancreatectomy alone		P value
	Median (mo)	n	Median (mo)	n	Median (mo)	n
Adam et al[57] (2006)	NA1	41	-	-	-	-	-
Yamada et al[58] (2006)	15.0	6	-	-	-	-	-
Gleisner et al[59] (2007)	5.9	17	-	-	-	-	-
Shrikhande et al[60] (2007)	7.9	10	-	-	-	-	-
De Jong et al[51] (2010)	17.7	NA	-	-	17.9	NA	0.730
De Jong et al[61] (2010)	13.02	14	-	-	-	-	-
Dünschede et al[49] (2010)	8.0	9	11	5	-	-	-
Seelig et al[62] (2010)	11.8	4	-	-	-	-	-
Klein et al[50] (2012)	13.0	7	-	-	26.5	13	NA
Tachezy et al[63] (2016)	14.5	69	7.5	69	-	-	< 0.001

¹Five-year survival of 20% was provided;

²The median survival of 25 patients with pancreatic ductal adenocarcinoma (PDAC) and cholangiocarcinoma.