Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer

Figure 3 Changes in mouse tumor size and weight after drug administration. A: The pictures show the size of the tumors in each group. Upper: control group. Middle: 100 mg/kg linalool group. Lower: 200 mg/kg linalool group. As concentration of linalool increased, the xenografted tumor size decreased macroscopically; B: Tumor weight after removal showed a significant decrease in the group of 200 mg/kg administration, compared to that of control group [expressed as geometric mean, n = 5 (control), 5 (100 mg/kg linalool), 6 (200 mg/kg linalool)], ^aP < 0.05 vs control group; one-way ANOVA followed by Dunnett’s test); C: No significant change was detected in serum AST and ALT level in each group; values are expressed as mean ± SD, n = 5 (control), 5 (100 mg/kg linalool), 6 (200 mg/kg linalool).