Disease-specific miR-34a as diagnostic marker of non-alcoholic steatohepatitis in a Chinese population

Table 2 General and biochemical parameters of non-alcoholic fatty liver and non-alcoholic steatohepatitis patients

Parameters	Group
	Control (n = 37)	NAFL (n = 17)	NASH (n = 31)
General parameters
Age (yr)	43.8 ± 1.3	37.1 ± 3.1	38.1 ± 2.3
Male n (%)	18 (48.6)	13 (76.4)	22 (71.0)
BMI (kg/m2)	21.4 ± 0.3	26.3 ± 0.91	27.2 ± 0.61
Biochemical parameters
ALT (U/L)	19.1 ± 2.4	47.8 ± 6.21	80.2 ± 10.412
AST (U/L)	18.8 ± 1.4	30.2 ± 3.8	51.5 ± 6.012
GGT (U/L)	19.1 ± 1.9	78.2 ± 36.8	128.2 ± 51.9
PLT (× 109/L)	200.4 ± 11.3	237.0 ± 14.8	207.3 ± 9.1
TC (mmol/L)	4.5 ± 0.1	4.7 ± 0.2	5.0 ± 0.1
TG (mmol/L)	0.8 ± 0.1	1.9 ± 0.31	2.2 ± 0.31
HDL (mmol/L)	1.4 ± 0.0	1.2 ± 0.11	1.2 ± 0.11
LDL (mmol/L)	2.4 ± 0.1	2.9 ± 0.21	2.9 ± 0.11

Data are expressed as mean ± SEM.

¹P < 0.05 vs the control group;

²P < 0.05 vs the non-alcoholic fatty liver (NAFL) group. NASH: Non-alcoholic steatohepatitis; BMI: Body mass index; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-glutamyl transpeptidase; PLT: Platelets; TC: Total cholesterol; TG: Triglycerides; HDL: High density lipoprotein; LDL: Low density lipoprotein.