IFIT1 polymorphisms predict interferon-&alpha; treatment efficiency for hepatitis B virus infection

doi:10.3748/wjg.v22.i44.9813

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2016; 22(44): 9813-9821
Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9813

Table 4 The association between single nucleotide polymorphisms and virological response by allele frequencies

SNP ID	Genotype	No./total¹	%	P²	OR	95%CI
rs303218	A	75/242	0.31	0.005³	1 (Reference)
	G	87/198	0.44		0.57	0.39-0.85
rs303215	T	93/227	0.41	0.045³	1 (Reference)
	C	69/217	0.32		1.49	1.01-2.20
rs11203109	T	109/341	0.32	0.020³	1 (Reference)
	C	37/81	0.46		0.56	0.34-0.92
rs303212	C	93/284	0.33	0.022³	1 (Reference)
	T	65/148	0.44		0.62	0.41-0.94

¹Number indicated the patients who responsed in the same group;

²P value was calculated by univariable logistic regression analysis;

³P < 0.05. SNP: Single nucleotide polymorphism.

Citation: Xie DY, Wang SM, Yang JM, Wang LH, Chen HY, Huai C, Shang J, Mao Q, Lei CL, Luo GH, Qian J, Lu DR. IFIT1 polymorphisms predict interferon-α treatment efficiency for hepatitis B virus infection. World J Gastroenterol 2016; 22(44): 9813-9821
URL: https://www.wjgnet.com/1007-9327/full/v22/i44/9813.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i44.9813