IFIT1 polymorphisms predict interferon-α treatment efficiency for hepatitis B virus infection

Table 3 Association between clinical factors and responses

Patient characteristics	Virological response			HBeAg seroconversion			Combined response			Sustained response
	R	NR	P value1	R	NR	P value1	R	NR	P value1	R	NR	P value1
Gender			0.113			0.081			0.0272			0.204
Male	55	108		39	163		20	163		39	163
Female	28	34		22	62		15	62		20	63
Age			0.151			0.723			0.924			0.116
Baseline ALT			0.070			0.0202			0.391			0.181
Baseline AST			0.205			0.113			0.443			0.279
Baseline HBV DNA level			0.121			0.554			0.617			0.217
HBV genotype			0.0122			0.0012			0.0382			2.37 × 10-42
Type A	3	5		1	7		1	7		1	7
Type B	42	52		38	56		19	75		37	57
Type C	10	5		5	10		5	10		6	9
Type B + C	22	58		11	69		7	73		10	70

¹P value was calculated by χ² test or Student's t-test depending on which variables were analyzed;

²P < 0.05. ALT: Alanine aminotransferase; AST: Aspartate transaminase; HBV: Hepatitis B virus; R: Response; NR: Non-response; HBeAg: Hepatitis B e antigen.