Association between Helicobacter pylori status and metachronous gastric cancer after endoscopic resection

Table 1 Baseline characteristics of patients in the Helicobacter pylori tested group n (%)

	H. pylori	H. pylori	H. pylori	P value
	negative group	persistent group	eradicated group
	(n = 95)	(n = 42)	(n = 120)
Sex
Male	74 (77.9)	29 (69.0)	86 (71.7)	0.454
Female	21 (22.1)	13 (31.0)	34 (28.3)
Age, mean (SD)	68.65 (8.86)	67.31 (9.12)	64.76 (10.10)	0.011
Follow-up period (mo), mean (SD)	36.18 (± 26.74)	33.29 (± 25.93)	32.78 (± 23.72)	0.149
Endoscopic mucosal atrophy	50 (52.6)	8 (19.0)	25 (20.8)	< 0.001
Intestinal metaplasia	63 (66.3)	18 (42.9)	32 (26.7)	< 0.001
Location of primary cancer
Upper	10 (10.5)	5 (11.9)	10 (8.3)	0.577
Middle	36 (37.9)	14 (33.3)	35 (29.2)
Lower	49 (51.6)	23 (54.8)	75 (62.5)
Macroscopic type of primary cancer
Elevated	40 (42.1)	122 (8.6)	57 (47.5)	0.177
Flat	13 (13.7)	5 (11.9)	9 (7.5)
Depressed	42 (37.0)	25 (59.5)	54 (45.0)
Diameter of primary cancer (cm), mean (SD)	14.24 (7.31)	13.83 (6.22)	13.67 (6.90)	0.978
Histology of primary cancer
Differentiated	93 (97.9)	38 (90.5)	118 (98.3)	0.032
Undifferentiated	2 (2.1)	4 (9.5)	2 (1.7)
ESD criteria
Absolute	73 (76.8)	33 (78.6)	95 (79.2)	0.636
Expended	18 (18.9)	5 (11.9)	19 (15.8)
Beyond expanded	4 (4.2)	4 (9.5)	6 (5.0)
Depth of primary cancer
Mucosa	89 (93.7)	40 (95.2)	111 (92.5)	0.819
Submucosa	6 (6.3)	2 (4.8)	9 (7.5)
Metachronous cancer recurrence	7 (7.4)	1 (2.4)	3 (2.5)	0.173

ESD: Endoscopic submucosal dissection; H. pylori: Helicobacter pylori.