Gene polymorphisms of pathogenic Helicobacter pylori in patients with different types of gastrointestinal diseases

doi:10.3748/wjg.v22.i44.9718

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Nov 28, 2016 (publication date) through Mar 2, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2016; 22(44): 9718-9726
Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9718

Table 1 The relationship between gastrointestinal diseases and Helicobacter pylori virulence factors

				VacA							IceA
	HomA	HomB	DuPA	VacAS2	VacAS1	VacM2	VacM1	Vaci2	Vaci1	CagA	IceA1	IceA2	OiPA
Chronic gastritis	+	++++	++	+	++++	+++	++	+	++++	++++	++	+	-
Dudenal ulcer	+	++++	++	-	++	++	+	+	++	++	+	+	++
Gastric ulcer	+	++++	+	+	+	+	+	-	-	+	+	+	++
Gastric cancer	+	++++	++	-	+	+	++	+	+++	++	+	+	++++

+: Incidence of disease, 0-20%; ++, 20%-40%; +++, 40%-60%; ++++, 60%-80%; +++++, 80%-100%.

Citation: Chen YL, Mo XQ, Huang GR, Huang YQ, Xiao J, Zhao LJ, Wei HY, Liang Q. Gene polymorphisms of pathogenic Helicobacter pylori in patients with different types of gastrointestinal diseases. World J Gastroenterol 2016; 22(44): 9718-9726
URL: https://www.wjgnet.com/1007-9327/full/v22/i44/9718.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i44.9718