Diabetes mellitus may affect the long-term survival of hepatitis B virus-related hepatocellular carcinoma patients after liver transplantation

Table 6 Multivariate proportional hazard model for tumor recurrence after liver transplantation in 1631 patients with hepatitis B virus-related hepatocellular carcinoma

Variables	B	SE	Wald	P value	OR (95%CI)
Venous invasion, absent vs present	0.780	0.124	39.825	0.000	2.182 (1.712-2.780)
Pre-LT antitumor therapy			11.093	0.005
Local therapy	-0.404	0.138	8.555	0.003	1.498 (1.143-1.964)
Resection	-0.285	0.230	1.536	0.215	0.752 (0.480-1.180)
GGT, ≤ 54 IU/L vs > 54 IU/L	0.360	0.131	7.559	0.006	1.433 (1.109-1.851)
TC, ≤ 1.7 mmol/L vs > 1.7 mmol/L	0.425	0.165	6.682	0.010	1.530 (1.108-2.113)
Serum AFP level, in ng/mL			27.634	0.000
< 200 vs 200-400	0.330	0.198	2.767	0.096	1.391 (0.943-2.051)
< 200 vs 400-1000	0.031	0.193	0.026	0.872	1.032 (0.707-1.506)
< 200 vs 1000-2000	0.378	0.212	3.161	0.075	1.459 (0.962-2.212)
< 200 vs > 2000	0.794	0.158	25.372	0.000	2.213 (1.625-3.015)
Number of tumor nodules			34.680	0.000
Single vs 2-3	0.377	0.144	6.885	0.009	1.457 (1.100-1.931)
Single vs≥ 4	0.763	0.130	34.674	0.000	2.144 (1.664-2.764)
Tumor size, in cm			110.647	0.000
≤ 3 vs 3-5	0.143	0.146	0.953	0.329	1.154 (0.866-1.537)
≤ 3 vs 5-7	1.112	0.150	55.206	0.000	3.042 (2.268-4.079)
≤ 3 vs > 7	1.402	0.158	78.831	0.000	4.065 (2.983-5.540)

LT: Liver transplantation; GGT: Gamma-glutamyl transpeptidase; AFP: α-fetoprotein.