Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK

doi:10.3748/wjg.v22.i43.9515

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2016; 22(43): 9515-9524
Published online Nov 21, 2016. doi: 10.3748/wjg.v22.i43.9515

Table 1 Semi-quantitative analysis of immunohistochemistry staining results for the expression of cannabinoid receptor type 1 and cannabinoid receptor type 2 receptors in mouse colon

Treatment	CB1	CB2
Control	0.05341338 ± 0.003277526	0.02905167 ± 0.008017215
DSS + Veh	0.16462150 ± 0.022503261^a	0.06704071 ± 0.013582954^a
DSS + SB	0.04293670 ± 0.008967458^c	0.02154800 ± 0.005380925^c
DSS + WIN55	0.13410205 ± 0.004475042^a	0.05116005 ± 0.006852826^a

Results are shown as mean ± SEM (n = 8 each group).

^aP < 0.05 vs control;

^cP < 0.05 vs dextran sulfate sodium (DSS) + vehicle (Veh). The semi-quantitative statistical analysis of the immunohistochemistry staining (AOD) was conducted using the ImagePro Plus 6.0 software. CB: Cannabinoid; SB: SB203580.

Citation: Feng YJ, Li YY, Lin XH, Li K, Cao MH. Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK. World J Gastroenterol 2016; 22(43): 9515-9524
URL: https://www.wjgnet.com/1007-9327/full/v22/i43/9515.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i43.9515