Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines

Table 3 MELK and IL11RA gene copy number and clinicopathological features of 68 gastric cancer patients

	MELK			IL11RA
	2 copies (n = 38)	≥3 copies (n = 30)	P value	2 copies (n = 55)	≥3 copies (n = 13)	P value
Age (yr) (mean ± SD)
> 50 (64.5 ± 6.9)	23	25	0.0748	39	9	0.7461
≤ 50 (42.5 ± 5.2)	15	5		16	4
Gender
Male	23	21	0.5781	34	9	0.7544
Female	15	9		21	4
Histopathology
Intestinal	23	20	0.7886	32	11	0.1110
Diffuse	15	10		23	2
Depth of tumor invasion
pT1-pT2	10	11	0.5137	18	3	0.4076
pT3-pT4	28	19		36	10
Lymph node metastasis
Absent	10	7	1.0000	11	6	0.1091
Present	28	23		44	7
Stage
I-II	25	17	0.6049	33	9	0.7525
III-IV	13	13		22	4