IRF5 regulates lung macrophages M2 polarization during severe acute pancreatitis in vitro

Figure 5 Comparison of the ability to reverse lung macrophage polarization by interferon regulatory factor 5 siRNA/IL-4. Lung macrophages were treated with interferon regulatory factor 5 (IRF5) siRNA/IL-4 for 4, 8, 16 and 24 h. The M1/M2 phenotypes were detected by real-time polymerase chain reaction. A: mRNA levels of M1 phenotypes in the macrophages; B: mRNA levels of M2 phenotypes in the macrophages. The statistical significance was analyzed when the two groups were compared in the same time point using indifferent t test. Error bars indicate the mean ± SE. ^aP < 0.05, ^cP < 0.01 vs control.