IRF5 regulates lung macrophages M2 polarization during severe acute pancreatitis in vitro

Figure 1 Histological examination of lung and pancrease stained with hematoxylin and eosin staining. A: Lung of control rats; B: Lung of acute pancreatitis (SAP) rats; C: Pancreas of control rats; D: Pancreas of SAP rats. There were no remarkable pathologic changes in control rats (A, C); Significant inflammatory cell infiltration was observed in the SAP group. The typical pathological changes of SAP associated with acute lung injury, including lung edema, necrosis, hemorrhage and neutrophil infiltration, were seen in SAP group (B). The histological changes of pancreas tissue such as the infiltration of neutropils, macrophages, interstitial edema, hemorrhage and focal necrotic areas were seen in the pancreas tissue of SAP group (D). Original magnification × 200 (A-D).