Molecular mechanism of action of anti-tumor necrosis factor antibodies in inflammatory bowel diseases

Figure 1 Expression of membrane-bound tumor necrosis factor in the gut. Gut tissue of patients with Crohn’s disease (CD) was cryo-frozen and stained for cell markers by immunofluorescence. Nuclei were counterstained with DAPI. A: Staining for mTNF (green). B: Staining for mTNF (green) and CD14 (red). Co-expressing cells are labeled with an arrow.