Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples

doi:10.3748/wjg.v22.i41.9214

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2016; 22(41): 9214-9221
Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9214

Table 3 Concordance in the detection of Helicobacter pylori and antibiotic resistance-mediating mutations between results obtained using biopsies vs stool samples from individual Campylobacter-like organisms-positive endoscopy patients

	Biopsy Specimens	Stool specimens	Concordance
Total analysed	n = 20	n = 20
H. pylori DNA positive	95% (n =19/20)	90% (n = 18/20)	85% (n = 17/20)
Clarithromycin resistant¹	52.9% (n = 9/17)	100.0% (n = 17/17)	52.9% (n = 9/17)
Fluoroquinolone resistant¹	23.5% (n = 4/17)	52.9% (n = 9/17)	35.3% (n = 6/17)

¹Only samples where H. pylori DNA was detected were analysed. H. pylori: Helicobacter pylori.

Citation: Brennan DE, Omorogbe J, Hussey M, Tighe D, Holleran G, O’Morain C, Smith SM, McNamara D. Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples. World J Gastroenterol 2016; 22(41): 9214-9221
URL: https://www.wjgnet.com/1007-9327/full/v22/i41/9214.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i41.9214