Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples

doi:10.3748/wjg.v22.i41.9214

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Nov 7, 2016 (publication date) through Feb 14, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2016; 22(41): 9214-9221
Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9214

Table 2 Molecular detection of Helicobacter pylori infection and resistance-mediating mutations using biopsies from CLO-positive endoscopy patients and stool samples of Urea Breath Test-positive patients

	Biopsy Specimens	Stool specimens	P value	95%CI
Total analysed	n = 55	n = 66
H. pylori DNA positive	98.2% (n = 54/55)	80.3 % (n = 53/66)	< 0.005	6.10-29.66
Clarithromycin resistant	51.9% (n = 28/54)	96.2 % (n = 51/53)	< 0.001	27.70-58.71
Fluoroquinolone resistant	9.3 % (n = 5/54)¹	13 % (n = 6/46)¹	0.55	-9.99-18.28

¹Fluoroquinolone and clarithromycin mutations present. H. pylori: Helicobacter pylori.

Citation: Brennan DE, Omorogbe J, Hussey M, Tighe D, Holleran G, O’Morain C, Smith SM, McNamara D. Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples. World J Gastroenterol 2016; 22(41): 9214-9221
URL: https://www.wjgnet.com/1007-9327/full/v22/i41/9214.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i41.9214