Impact of IL28B and OAS gene family polymorphisms on interferon treatment response in Caucasian children chronically infected with hepatitis B virus

Table 4 Association of OAS haplotypes with treatment response

Haplotype	CR	No-CR	P value	OR (95%CI)	PR	No-PR	P value	OR (95%CI)
A A A A	0.11	0.16	0.402	0.60 (0.18-1.98)	0.16	0.00	0.041	NA
A A G A	0.03	0.05	0.473	0.47 (0.06-3.78)	0.05	0.00	0.283	NA
A A G G	0.17	0.35	0.031	0.35 (0.13-0.92)	0.21	0.57	0.002	0.21 (0.07-0.61)
A G G G	0.24	0.12	0.156	2.11 (0.74-6.00)	0.17	0.13	0.543	1.55 (0.37-6.48)
G A G G	0.28	0.03	0.0003	11.96 (2.38-59.97)	0.16	0.05	0.173	3.91 (0.48-31.8)
G G G G	0.05	0.17	0.046	0.24 (0.05-1.06)	0.15	0.05	0.194	3.70 (0.45-30.25)

Data are presented as the haplotype frequency; NA: Not applicable.