Neuroendocrine neoplasms of liver - A 5-year retrospective clinico-pathological study applying World Health Organization 2010 classification

Figure 3 D1/D2 and D2/D3 neuroendocrine neoplasms. A: D1/2 - liver biopsy showing clusters of tumor cells with uniform nuclei and no conspicuous mitotic activity (H&E × 200); B: Tumor cells displaying Ki-67 index of approximately 5% (immunohistochemistry × 200); C: D2/D3 shows tumor cells arranged in trabeculae and focal acinar pattern with mildly pleomorphic nuclei (H&E × 200); D: Tumor cells displaying Ki-67 index of approximately 30% (immunohistochemistry × 200).