Antioxidant and anti-inflammatory action of melatonin in an experimental model of secondary biliary cirrhosis induced by bile duct ligation

Figure 2 Mean hepatosomatic and splenosomatic index values in the different experimental groups. All results are expressed as mean ± SD error. Significant difference existed between the BDL and control groups (CO and CO + Mel) (^eP < 0.001). Significant difference existed between the BDL and BDL + Mel groups (^fP < 0.001). CO: Control; CO + Mel: Control + melatonin; BDL: Bile duct ligation; BDL + Mel: Bile duct ligation + melatonin; HSI: Hepatosomatic index; SSI: Splenosomatic index.