Copyright
©The Author(s) 2016.
World J Gastroenterol. Oct 28, 2016; 22(40): 9012-9021
Published online Oct 28, 2016. doi: 10.3748/wjg.v22.i40.9012
Published online Oct 28, 2016. doi: 10.3748/wjg.v22.i40.9012
Dosage of thioguanine | 6-TGN level | Observed NRH | Ref. |
About 20 mg per day (18-24 mg) | 278 (68-492) | 0% (0/12) | [20] |
20 mg per day | 564 ± 278 | 0% (0/28) | [18] |
20 mg per day | 802 (106-1092) | 0% (0/13) | [47] |
About 21 mg per day (0.3 mg/kg) | 464 (65-1199) | 6% (7/111) | [48] |
40 mg per day | 807 (105-2545) | 0% (0/11) | [16] |
About 40 mg per day (estimated) | 1230 (530-2310) | 62% (16/26) | [15] |
40-80 mg per day | Unknown | 36% (16/45) | [45] |
- Citation: Meijer B, Mulder CJ, Peters GJ, van Bodegraven AA, de Boer NK. Efficacy of thioguanine treatment in inflammatory bowel disease: A systematic review. World J Gastroenterol 2016; 22(40): 9012-9021
- URL: https://www.wjgnet.com/1007-9327/full/v22/i40/9012.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i40.9012