Liver-targeted hydrodynamic gene therapy: Recent advances in the technique

doi:10.3748/wjg.v22.i40.8862

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Oct 28, 2016 (publication date) through Jul 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Therapeutics Advances

World J Gastroenterol. Oct 28, 2016; 22(40): 8862-8868
Published online Oct 28, 2016. doi: 10.3748/wjg.v22.i40.8862

Table 1 Non-viral gene delivery systems toward the liver

Method	Functional component
Lipids	Cationic lipids
Polymers	Cationic polymers
Proteins	Natural or chemically modified proteins in cationic nature
Peptides	Lysine or arginine residues in peptides
Needle injection	Mechanic force
Gene gun	Pressure
Electroporation	Electric pulse
Sonoporation	Ultrasound
Hydrodynamic delivery	Hydrodynamic pressure

Citation: Yokoo T, Kamimura K, Abe H, Kobayashi Y, Kanefuji T, Ogawa K, Goto R, Oda M, Suda T, Terai S. Liver-targeted hydrodynamic gene therapy: Recent advances in the technique. World J Gastroenterol 2016; 22(40): 8862-8868
URL: https://www.wjgnet.com/1007-9327/full/v22/i40/8862.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i40.8862