Appraisal of needle-based confocal laser endomicroscopy in the diagnosis of pancreatic cysts

Table 1 Outcome, diagnostic accuracies, and risk of pancreatitis for major trials investigating role of endoscopic ultrasound-guided needle based confocal laser endomicroscopy needle based confocal laser endomicroscopy in diagnosis of pancreatic cystic lesions

Study	Outcome	Patients, n	Surgery, n (%)	SN	SP	PPV	NPV	Accuracy	Pancreatitis rate (%)
INSPECT[21]	Neoplastic cystic lesions	Total: 66	14 (21.2)	59	100	100	50	71	3.0
DETECT[17]	Mucinous cystic lesion	Total: 30	2 (6.0)	80	100	100	80	89	6.62
		High certainty: 181
CONTACT[22]	Serous cystadenoma	Total: 31	7 (22.5)	69	100	100	82	87	3.2

¹High-certainty patients included in analysis of diagnostic accuracy;

²Patient underwent both, needle based cystoscopy and confocal endomicroscopy. SN: Sensitivity; SP: Specificity; PPV: Positive predictive value; NPV: Negative predictive value.