Copyright
©The Author(s) 2016.
World J Gastroenterol. Jan 28, 2016; 22(4): 1650-1663
Published online Jan 28, 2016. doi: 10.3748/wjg.v22.i4.1650
Published online Jan 28, 2016. doi: 10.3748/wjg.v22.i4.1650
DAA agent or combination | Issues in renal dysfunction |
Sofosbuvir | Contraindication in GFR < 30 mL/min due to insufficient safety data[127] |
Simeprevir | No dose adjustment[75] |
Ledipasvir | Limited data; no theoretical concerns[127] |
PTV/r + OMB + DSV | Safe and effective and no dose adjustment in ESRD[100] |
Daclatasvir | No dose adjustment[78] |
Elbasvir/Grazoprevir | Safe and effective and no dose adjustment in ESRD[101] |
- Citation: Belga S, Doucette KE. Hepatitis C in non-hepatic solid organ transplant candidates and recipients: A new horizon. World J Gastroenterol 2016; 22(4): 1650-1663
- URL: https://www.wjgnet.com/1007-9327/full/v22/i4/1650.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i4.1650