Diagnosing gastrointestinal illnesses using fecal headspace volatile organic compounds

Table 5 Diagnosis of other gastroenterological conditions by fecal volatile organic compounds detection

Ref.	Year	Category	Disease (:control)	AUC	Accuracy	Sensitivity	Specificity	Sample No.	Control No.
Di Cagno et al[46]	2009	Celiac disease	Treated celiac disease	-	-	-	-	7	7
Di Cagno et al[46]	2009	Celiac disease	Untreated celiac disease	-	-	-	-	7	7
Di Cagno et al[46]	2009	Celiac disease	Treated:Untreated celiac disease	-	-	-	-	7	7
Garner et al[73]	2009	Enterocolitis	Necrotizing enterocolitis	-	-	-	-	6	7
Raman et al[74]	2013	Liver disease	NAFLD	-	-	-	-	30	30
Bjarnason et al[75]	2009	Liver disease	NAFLD	-	-	-	-	7	9
Covington et al[76]	2012	Radiation toxicity	Low GI pelvic radiation toxicity	-	90%	-	-	10	11
Covington et al[76]	2012	Radiation toxicity	High GI pelvic radiation toxicity	-	90%	-	-	11	12
Covington et al[76]	2012	Radiation toxicity	Low GI pelvic radiation toxicity	-	80%	-	-	8	11
Covington et al[76]	2012	Radiation toxicity	High GI pelvic radiation toxicity	-	80%	-	-	10	12

If no control is specified, the comparison is against a healthy control. NAFLD: Nonalcoholic fatty liver disease; AUC: Area under the curve; GI: Gastrointestinal.