Retrospective Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Oct 21, 2016; 22(39): 8798-8805
Published online Oct 21, 2016. doi: 10.3748/wjg.v22.i39.8798
Table 1 Clinicopathological characteristics of 116 hepatocellular carcinoma patients treated by curative resection, stratified by COX-2 and EP1 receptor expression
VariableCOX-2
P valueEP1 receptor
P value
Low expressionHigh expressionLow expressionHigh expression
(n = 62)(n = 54)(n = 73)(n = 43)
Gender, M/F48/1445/90.42660/1333/100.477
Age (yr)46.9 ± 10.847.9 ± 11.50.30846.6 ± 11.147.3 ± 11.20.486
HbsAg
Negative10100.7341190.420
Positive52446234
Liver cirrhosis
No10100.7341460.472
Yes52445937
AFP (ng/mL)
< 40041440.06256290.276
≥ 40021101714
Edmondson grade
I-II26370.00446170.014
III–IV36172726
Child-Pugh class
A43480.77360310.201
B11141312
Tumor capsule
Complete37340.71744270.788
Incomplete25202916
Tumor size (cm)5.7 (3-7)6.6 (4-8.6)0.1345 (3.5-7)6 (3.7-8.5)0.207
Albumin (g/L)41.1 ± 4.440.4 ± 4.60.43441.5 ± 4.340.2 ± 4.50.134
Platelet count (109/L)167.9 (107.3-205.3186.6 (136.3-230)0.136178.9 (107.3-205.3186.6 (136.3-230)0.833
AST (U/L)56.6 (28.3-61)55.6 (27-60)0.92438 (27-60)44 (30.5-61.5)0.737
ALT (U/L)54.8 (28-56)62.7 (24.8-57.9)0.53937(27-56)38(27-55)0.917
Total bilirubin (μmol/L)14.08 (8.9-18.4)14.3 (9.4-15.3)0.91211.9(9.35-16.6)13.4(9-17.7)0.580