Predicting malignant transformation of esophageal squamous cell lesions by combined biomarkers in an endoscopic screening program

Table 3 The correlation coefficients for p53, CA19-9, CEA and selected variables

Variables	Spearman's correlation coefficient
	p53	CA19-9	CEA
Age	-0.0811	-0.065	-0.0931
School year	0.197	0.139	0.213
Alcohol drinking index	-0.050	-0.056	-0.021
Smoking index	-0.038	-0.050	-0.003
Family history of esophageal cancer	0.020	-0.078	-0.035
Degree of esophageal lesions3	0.2872	0.3262	0.4552
p53	1	0.3252	0.3742
CA19-9		1.000	0.5032
CEA			1.000

¹Correlation is significant at the 0.05 level (2-tailed);

²Correlation is significant at the 0.01 level (2-tailed);

³The variable definitions for the degree of esophageal lesions were: 1, normal control; 2, basal cell hyperplasia; 3, low-grade dysplasia; 4, high-grade dysplasia; 5, invasive squamous cell cancer.