Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury

Figure 3 Hematoxylin-eosin staining of liver sections from rats fed ethanol (A) or ethanol + 0. 36% guanidinoacetate (B) for 6-wk. There is a diffuse inflammatory infiltrate in the liver from the rat fed ethanol plus guanidinoacetate. Green arrows indicate lipogranulomas, green circle indicates an inflammatory cell foci, Scale bar = 100 microns. PT: Portal triad, CV: Central vein.