Childhood chronic gastritis and duodenitis: Role of altered sensory neuromediators

Figure 4 Calcitonin gene-related peptide measurements in the control (n = 30) and study (n = 52) groups. A: The calcitonin gene-related peptide (CGRP) levels were lower in the gastric mucosa from sites with severe (S1, b) and less severe (S2, a) gastritis than in the control group in the first and second extractions (P = 0.011, P = 0.031, first extraction, respectively; P = 0.002, P = 0.004, second extraction, respectively). Moreover, in the study group, CGRP levels were lower in S1 than in S2 samples in both the first and second extractions (P = 0.037 and P = 0.046, respectively); B: No significant differences in the CGRP levels were observed between H. pylori (+) and H. pylori (-) patients in the first and second extractions; C: CGRP levels were significantly higher in patients with low-grade gastritis. H. pylori: Helicobacter pylori.