Defining response to radiotherapy in rectal cancer using magnetic resonance imaging and histopathological scales

Table 12 Comparison of outcomes between good and poor responders

Ref.	Year	Local recurrence (LR)	P < 0.05	Distant recurrence (DR)	P < 0.05	Progression disease-free survival (DFS)	P < 0.05	Disease-free survival (DFS)	P < 0.05	Overall survival (OS)	P < 0.05	Conclusion
Shihab et al[52]	2011	Better in GR	No	Better in GR	Yes							Good responders have better, statistically significant outcomes for DR but have better, non significant LR
Patel et al[5] and Patel et al[7]	2011 and 2012	Better in GR	No					Better in GR	Yes	Better in GR	Yes	Good responders have better, statistically significant outcomes for DFS and OS but have better, non significant outcomes for LR
Yu[53]	2014					Better in GR	Yes			Better in GR	Yes	Good responders have better, statistically significant outcomes for DFS and OS

GR: Good responders; NC: No statistical comparison made; DNI: Data not interpretable.